Published Articles

High-Frequency Oscillations Recorded on the Scalp of Patients with Epilepsy Using Tripolar Concentric Ring Electrodes

W. Besio, I. Martinez-Juarez, O. Makeyev, J. Gaitanis, A. Blum, R. Fisher, A. Medvedev

Electroencephalography (EEG) is a noninvasive means for recording electrical activity of the brain. We have developed tripolar concentric ring electrodes (TCREs) and have shown that TCREs provide higher signal-to-noise ratios, higher spatial resolution, and less mutual information than conventional disc electrodes. This paper describes the results of a clinical study of patients with epilepsy to determine if high-frequency oscillations (HFOs) were present in EEG recorded with TCREs.

Near Real-time Computer Assisted Surgery for Brain Shift Correction using Biomechanical Models

K. Sun, T.S. Pheiffer, A.L. Simpson, J.A. Weis, R.C. Thompson, M.I. Miga

Brain deformation during surgery compromises the fidelity of image-guided tumor resection procedures.  This paper presents a comprehensive framework to intraoperatively account for volumetric brain deformations within image-guided surgery systems using only measurements of cortical surface ‘shift’…

Effective CPR Procedure with Real Time Evaluation and Feedback Using Smartphones

N.K. Gupta, V. Dantu, R. Dantu

Timely CPR can mean the difference between life and death. A trained person may not be available at emergency sites to give CPR. Normally, a 9-1-1 operator gives verbal instructions over the phone to a person giving CPR. In this paper, we discuss the use of smartphones to assist in administering CPR more efficiently and accurately. The two important CPR parameters are the frequency and depth of compressions…

μ-Foil Polymer Electrode Array for Intracortical Neural Recordings

F. Ejserholm, P. Kohler, M. Granmo, J. Schouenborg, M. Bengtsson, L. Wallman

We have developed a multichannel electrode array, termed μ-foil, that comprises ultrathin and flexible electrodes protruding from a thin foil at fixed distances. This study is an early evaluation of technical aspects and performance of this electrode array in acute in vitro/in vivo experiments. The in vivo acute measurements showed…

A Remote-Controlled Airbag Device Can Improve Upper Airway Collapsibility by Producing Head Elevation with Jaw Closure in Normal Subjects Under Propofol Anesthesia

S. Ishizaka, S. Moromugi, M. Kobayashi, H. Kajihara, K. Koga, H. Sugahara, T. Ishimatsu, S. Kurata, J. Kirkness, K. Oi, T. Ayuse

Upper airway collapse is a dangerous problem in sedated patients who are undergoing surgery or imaging studies, and in people with sleep apnea. This paper presents the result of two clinical trials that examined the effect of a remote-controlled airbag device to control head, neck and jaw position and prevent airway collapse in patients who are sedated for surgery or diagnostic imaging, and for prevention of sleep apnea. The results of both studies demonstrate the promise of the device…

Urine Flow Dynamics Through Prostatic Urethra With Tubular Organ Modeling Using Endoscopic Imagery

T. Ishii, Y. Kambara, T. Yamanishi, Y. Naya, T. Igarashi

Visualization of urine flow behavior through the prostatic urethra. A sequence of cystourethroscopic video images during the withdrawal maneuver was processed to generate a 3D model of the intraluminal shape of the urethra. Computation of urine flow dynamics in the urethra would unveil the critical lesions responsible for voiding dysfunction…

A Method to Standardize Quantification of Left Atrial Scar From Delayed-Enhancement MR Images

R. Karim, A. Arujuna, R.J. Housden, J. Gill, H. Cliffe, K. Matharu, J. Gill, C.A. Rindaldi, M. O'Neill, D. Rueckert, R. Razavi, T. Schaeffter, K. Rhode

Standardization of quantification for left-atrial scar will allow the selection of patients who are predicted to respond well to ablation procedures for cardiac arrhythmias. This could improve the success rate of such procedures and reduce recurrence of arrhythmias. An algorithm to standardize quantification is proposed…

An Adaptive Home-Use Robotic Rehabilitation System for the Upper Body

A. Dowling, O. Barzilay, Y. Lombrozo, A. Wolf

The research objective was to create a home-use robotic rehabilitation system. Data was obtained in real-time from a Microsoft Kinect™ and a wireless surface EMG system. Subjects completed visual follow exercise tasks in a 3D visual environment. Data from two training exercises were used to generate a neural network, which was used to simulate the subject’s individual performance. A wearable arm robot prototype was built that was able to mimic changes in a subject’s elbow angle in real-time…

Scope Statement

We focus on innovative solutions to healthcare needs from biomedical engineering, clinical engineering, and medical communities that bridge the engineering and clinical worlds. JTEHM's unique scope is original work at the intersection of engineering and clinical translation.

The journal’s focus is interdisciplinary collaborations among researchers, healthcare providers, and industry. We publish results and best practices from these translational efforts and serve as a community hub for researchers, clinicians, and developers who are addressing challenges in technology development, commercialization, and deployment for better global healthcare. Our ultimate goal is to improve the practice of engineering in translational medicine and to serve as a focal point for the nascent community. Our interactive content includes video, lively commentary, blogs, and other features to engage our clinical and engineering communities.