Featured Articles

A Bayesian Algorithm for Anxiety Index Prediction Based on Cerebral Blood Oxygenation in the Prefrontal Cortex Measured by Near Infrared Spectroscopy

Y. Fukuda, Y. Ida, T. Matsumoto, N. Takemura, K. Sakatani

Stress-induced psychological and somatic diseases are virtually endemic nowadays. Written self-report anxiety measures are available; however, these indices tend to be time consuming to acquire. For medical patients, completing written reports can be burdensome if they are weak, in pain, or in acute anxiety states. Consequently, simple and fast non-invasive methods for assessing stress response from neurophysiological data…


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Y FukudaY Fukuda
Mr. Fukuda received a B.E. degree from the Department of Electrical Engineering and Bioscience, Waseda University, Tokyo, Japan, and is currently pursuing an M.S. degree at the same institution. His current research interests include Bayesian machine learning for prediction problems with Monte Carlo implementations, using Near Infrared Spectroscopy data.

Y IdaY Ida
Mr. Ida received a B.E. degree from the Department of Electrical Engineering and Bioscience, Waseda University, Tokyo, Japan, and is currently pursuing an M.S. degree at the same institution. His current research interests include sentiment analysis and relational model by Bayesian method. He is working on handling relational data with side-information via Bayesian model.

T MatsumotoT Matsumoto
Dr. Matsumoto is a professor in the Faculty of Advanced Science and Engineering, Waseda University. He has had visiting positions at U.C. Berkeley and Cambridge University, U.K. His research interests are Bayesian machine learning with Monte Carlo implementations and Bootstrap method, with target data including biological data, image data, and time series data. He also has interests in non-parametric priors for Bayesian learning.

N TakemuraN Takemura
Mr. Takemura received a B.Sc. degree in engineering in 2003 and a M.Sc. degree in Informatics in 2005, from Kyoto University, Japan. He is currently a researcher in College of Engineering, Nihon University, Japan. His research interests include neuroscience and biomedical engineering.

K SakataniK Sakatani
Dr. Sakatani is a Professor at Nihon University College of Engineering and School of Medicine. He is also a Board-certified Neurosurgeon in Japan. His research interests include biomedical engineering, optical engineering, neuroimaging, and neuroscience.

The Effect of Light Conditions on Photoplethysmographic Image Acquisition Using a Commercial Camera

H. Liu, Y. Wang, L. Wang

Cameras embedded in consumer devices have previously been used as physiological information sensors. The waveform of the PPGi signals may be significantly affected by the light spectra and intensity. The purpose of this paper is to evaluate the performance of PPGi waveform acquisition in the red, green, and blue channels using a commercial camera in different light conditions…


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Current and Future Challenges in Point-of-Care Technologies: A Paradigm-Shift in Affordable Global Healthcare with Personalized and Preventive Medicine

A.P. Dhawan, W.J. Heetderks, M. Pavel, S. Acharya, M. Akay, A. Mairal, B. Wheeler, C.C. Dacso, T. Sunder, N. Lovell, M. Gerber, M. Shah, S.G. Senthilvel, M.D. Wang, B. Bhargava

Pre-Publication POCHT 2013 White Paper
This paper summarizes the panel discussion at the IEEE Engineering in Medicine and Biology Point of Care Healthcare Technology Conference (POCHT 2013) held in Bangalore India from Jan 16-18, 2013. Modern medicine has witnessed interdisciplinary technology innovations in healthcare with a continuous growth in life expectancy across the globe. However, there is also a growing global concern on the affordability of rapidly rising healthcare costs…


Complete bios of the authors will be on Xplore

A DharwanA Dhawan
Dr. Dhawan. obtained his bachelor’s and master’s degrees from the Indian Institute of Technology, Roorkee, and his Ph.D. from the University of Manitoba. His research interests lie in medical imaging, medical image analysis, point-of-care technologies, pattern recognition and computer-aided-diagnosis.

W HeetderksW Heetderks
Dr. Heetderks received the Ph.D. degree in Bioengineering from The University of Michigan. He received the MD degree from the University of Miami and is certified in Internal Medicine. Before joining NIBIB he was at the National Institute of Neurological Disorders and Stroke where he directed the neural prosthesis program.

M PavelM Pavel
Dr. Pavel is the Program Director of Smart Health and Wellbeing at the National Science Foundation. His current research is at the intersection of computational modeling of complex behaviors of biological systems, engineering, and cognitive science with a focus on information fusion, pattern recognition, augmented cognition, and the development of multimodal and perceptual human-computer interfaces.

S AcharyaS Acharya
Dr. Acharya was the chief architect of a new and innovative graduate program in bioengineering innovation and design that has attracted top engineering students, outside funding, and numerous awards. He also runs a program in global medical technology innovation, which focuses on developing appropriate healthcare technologies for resource-restrained customers globally.

M AkayM Akay
Dr. Akay is the founding chair of the Biomedical Engineering Department and the John S. Dunn professor of biomedical engineering at the University of Houston. He currently serves on the advisory board of several international journals and on several NIH and NSF review panels.

A MairalA Mairal
Dr. Mairal is the Director, Global Exchange Programs, Stanford University. He is a Co-founder and Executive Vice President of Orbees Medical, a consulting firm serving medical device industry in the U.S., Europe, and Asia. He serves on the boards of several for-profit and non-profit organizations and is a Charter Member at EPPIC.

B WheelerB Wheeler
Prof. Wheeler’s research interests lie in the application of electrical engineering methodologies to neuroscience. His work influenced the development of neural spike sorting technologies, demonstrated that microelectrode array recording from brain slices was possible and productive, and has been a leader in the development of lithography to control cells, especially neurons, in culture.

C DacsoC Dacso
Dr. Dacso holds degrees from the University of Pennsylvania (BA, MA 1972), Baylor College of Medicine (MD 1975), University of Texas (MPH, 1980) and Pepperdine University (MBA 1990). Dr. Dacso’s research and development focuses on new technologies that integrate information and support for patients with chronic disease, particularly in under-resourced communities. Current work includes remote patient monitoring systems for congestive heart failure, asthma, exercise, and diabetes.

T SunderT Sunder
Dr. Sunder is a Senior Consultant and Cardiothoracic and Transplant Surgeon at the Apollo Group of Hospitals, Chennai. He is interested in predictive health analysis and pattern recognition and is involved in updating the electronic medical records and hospital information systems at Apollo Hospitals, Chennai.

N LovellN Lovell
Prof. Lovell is currently at the Graduate School of Biomedical Engineering UNSW where he holds a position of Scientia Professor. His research work has covered areas of expertise ranging from cardiac modeling, telehealth technologies, biological signal processing, and visual prosthesis design.

M GerberM Gerber
Mr. Gerber is the Senior R&D director for Medtronic India. He is the Core Team Leader (program general manager) for complex neurostimulation systems and new therapy development. His specialties include strategy development, program management, therapy and product development, merging science and business, general management, intellectual property and strategic problem solving.

M ShahM Shah
Mr. Shah is the Vice President, South Asia and Managing Director, India Medtronic. He joined Medtronic as the Managing Director of India Medtronic in October, 2004. Mr. Shah has over 28 years’ experience in leadership, sales & marketing and corporate planning positions in Healthcare, Specialty Chemicals, Telecommunications and Petrochemicals.

S SenthilvelS Senthilvel
Dr. Senthilvel is Subject Matter Expert and Industry Solutions Leader, Healthcare and Public Sector, IBM India. He serves as a member of the industry experts panel in defining curriculum and conducting train-the-trainer programs in healthcare and bio-informatics and pharmaceutical biotechnology at various Indian engineering universities.

M WangM Wang
Dr. Wang is a tenured associate professor in The Wallace H. Coulter Joint Department of Biomedical Engineering Department at Georgia Institute of Technology and Emory University. Dr. Wang’s research interest is biomedical and health informatics such as clinical biomarker identification using –omic and next generation sequencing; molecular imaging informatics; therapeutics modeling for nanomedicine; and data analytics of personal health record for prevention.

B BhargavaB Bhargava
Dr. Bhargava is one of the foremost leaders in biomedical innovation, public health, medical education and medical research in India. He is currently developing the Chest Compression Device for Sudden Cardiac Death patients, funded by the Wellcome Trust. He is also providing leadership for a creative disease prevention, early detection and transport system for sick cardiac patients.

See Additional Current Articles

Published Articles

Pre to Intraoperative Data Fusion Framework for Multimodal Characterization of Myocardial Scar Tissue

A. R. Porras, G. Piella, A. Berruezo, J. Fernandez-Armenta, A. F. Frangi

This paper presents a framework to analyze and combine information from delayed enhancement magnetic resonance imaging (DE-MRI) and electro-anatomical mapping data. This information is used to perform electrical, mechanical and image-based characterization of the myocardium. The proposed framework has the potential to guide and monitor delivery of radiofrequency ablation of ventricular tachycardia…


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A PorrasA Porras
Mr. Porras is currently pursuing a Ph.D. degree with Universitat Pompeu Fabra, Barcelona. His main research interest is biomedical data/images integration for motion and deformation estimation of the heart.

G PiellaG Piella
Dr. Piella is with the Department of Technology, Universitat Pompeu Fabra, Barcelona. Her work has focused on multiresolution analyses, adaptive wavelets, geometrical image processing, and image fusion and registration.

A BerruezoA Berruezo
Dr. Berruezo is with the Arrhytmia Section, Thorax Institute of Hospital Clínic de Barcelona, Universitat de Barcelona. He is involved in several research projects related with atrial brillation, cardiac resynchronization therapy, and ventricular arrhythmias, with ventricular tachycardia ablation as his main area of interest.

J Fernandez-ArmentaJ Fernandez-Armenta
Dr. Fernandez-Armenta received his Ph.D. degree from the Universitat de Barcelona, Barcelona, Spain, in 2014. He has been awarded with the European Accreditation in Interventional Cardiac Electrophysiology and Cardiac Pacing. His main research fields are ventricular arrhythmias and sudden cardiac death.

A FrangiA Frangi
Mr. Frangi is currently a Professor of Biomedical Image Computing with the University of Shefeld, Shefeld, U.K. His main research interests are in medical image computing, medical imaging, and image-based computational physiology.

Controlling knee swing initiation and ankle plantarflexion with an active prosthesis on level and inclined surfaces at variable walking speeds

N. P. Fey, A. M. Simon, A. J. Young, L. J. Hargrove

Improving lower-limb prostheses is important to enhance the mobility of amputees. The purpose of this study was to introduce an impedance-based control strategy (consisting of four novel algorithms) for an active knee and ankle prosthesis and test its generalizability across multiple walking speeds, walking surfaces and users…


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N FeyN Fey
Dr. Fey is currently a Post-Doctoral Research Fellow with the Center for Bionic Medicine, Rehabilitation Institute of Chicago, Chicago, IL, USA. He also has an appointment with the Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago. His overall research interest is to identify how given task demands and lower-limb assistive devices contribute to human motor control and biomechanics.

A SimonA Simon
Dr. Simon is a Biomedical Engineering Manager in the Center for Bionic Medicine at the Rehabilitation Institute of Chicago, and a Research Assistant Professor in the Department of Physical Medicine and Rehabilitation at Northwestern University. Her research interests include overcoming clinical challenges associated with the application of advanced pattern recognition myoelectric control systems for both upper- and lower-limb amputees.

A YoungA Young
Mr. Young is currently working toward the Ph.D. degree at Northwestern University in the Center for Bionic Medicine at the Rehabilitation Institute of Chicago. His research interests include neural signal processing and pattern recognition using advanced machine learning techniques for control of myoelectric prosthesis for the upper and lower limb.

L HargroveL Hargrove
Dr. Hargrove is Director of the Neural Engineering for Prosthetics and Orthotics Laboratory at CBM. He is also a Research Assistant Professor in the Department of Physical Medicine and Rehabilitation at Northwestern University. His research interests include pattern recognition, biological signal processing and myoelectric control of powered prostheses.

Experimental Procedure for Determination of the Dielectric Properties of Biological Samples in the 2-50 GHz Range

E. Odelstad, S. Raman, A. Rydberg, R. Augustine

The objective of this paper was to test and evaluate an experimental procedure for providing data on the complex permittivity of different cell lines in the 2–50-GHz range at room temperature, for the purpose of future dosimetric studies. The complex permittivity measurements were performed on cells suspended in culture medium using an open-ended coaxial probe…


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E OdelstadE Odelstad
Mr. Odelstad is currently pursuing the Ph.D. degree in space and plasma physics with Uppsala University and the Swedish Institute of Space Physics, Kiruna, Sweden. His current research interests include the evolution of the plasma environment around comets and spacecraft plasma interactions.

S RamanS Raman
Dr. Raman is currently a Post-Doctoral Researcher in Solid-State Electronics with the Angstrom Laboratory, Uppsala University, Uppsala, Sweden. His research interests include designing of planar antennas, planar microwave devices, bioelectromagnetics, and microwave material characterization.

A RydbergA Rydberg
Dr. Rydberg heads the Microwave Group with the Department of Engineering Science, Uppsala University. He has authored and co-authored more than 220 publications in the area of micro and millimeterwave antennas, sensors, solid-state components and circuits, and holds three patents in the areas.

R AugustineR Augustine
Dr. Augustine is a Researcher with Uppsala University, Uppsala, Sweden. He has authored and co-authored more than 35 publications, including journals and conferences. His current research interests include designing of wearable antennas, BMD sensors, dielectric characterization, bioelectromagnetism, noninvasive diagnostics, and biological healing effects of RF in in vitro and in vivo systems.

High-Frequency Oscillations Recorded on the Scalp of Patients with Epilepsy Using Tripolar Concentric Ring Electrodes

W. Besio, I. Martinez-Juarez, O. Makeyev, J. Gaitanis, A. Blum, R. Fisher, A. Medvedev

Electroencephalography (EEG) is a noninvasive means for recording electrical activity of the brain. We have developed tripolar concentric ring electrodes (TCREs) and have shown that TCREs provide higher signal-to-noise ratios, higher spatial resolution, and less mutual information than conventional disc electrodes. This paper describes the results of a clinical study of patients with epilepsy to determine if high-frequency oscillations (HFOs) were present in EEG recorded with TCREs…


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W BesioW Besio
Dr. Besio is an Associate Professor in the Electrical, Computer, and Biomedical Engineering Department at the University of Rhode Island. His laboratory performs research to develop innovative biomedical instrumentation for diagnosis and therapies for enhancing the lives of persons with disease and disability.

I Martinez-JuarezI Martinez-Juarez
Dr. Martínez-Juárez is a Neurologist-Epileptologist and Head of the Epilepsy Clinic, National Institute of Neurology and Neurosurgery, Mexico, Professor of Clinical Epileptology Fellowship, National Autonomous University of Mexico (UNAM) and National Institute of Neurology and Neurosurgery, Mexico. Her research interests are in juvenile myoclonic epilepsy and genetics of epilepsy.

O MakeyevO Makeyev
Dr. Makeyev is with the Department of Electrical, Computer, and Biomedical Engineering at the University of Rhode Island, Kingston, RI. His broad research interests include development and application of computational intelligence and statistics based signal processing and pattern recognition methods to engineering problems with an emphasis on biomedical engineering.

J GaitanisJ Gaitanis
Dr. Gaitanis is an Associate Professor of Neurology and Pediatrics (clinical) at the Warren Alpert Medical School of Brown University and the Director of Pediatric Epilepsy at Hasbro Children’s Hospital. His research interests include brain malformations, pediatric epilepsy, and use of electroencephalography in the diagnosis of neurological conditions.

A BlumA Blum
Dr. Blum is an Associate Professor of Neurology at the Alpert Medical School of Brown University. His current research interests focus upon epilepsy co-morbidities, particularly psychiatric and cognitive concerns, epilepsy in older populations, and the pathophysiology of epileptic seizures including mechanisms germane to SUDEP, sudden unexplained death in epilepsy.

R FisherR Fisher
Dr. Fisher is is Maslah Saul MD Professor and Director of the Stanford Epilepsy Center. He received the Ambassador Award from the International League Against Epilepsy, the 2005 AES Service Award, and the 2006 Annual Clinical Research Award. He has served on the Board of the ILAE and as Editor-in-Chief of the Journal, Epilepsia. His research is on new devices to treat epilepsy.

A MedvedevA Medvedev
Dr. Medvedev is a neurophysiologist and computational neuroscientist. His expertise includes systems electrophysiology, high density EEG, source localization, near-infrared optical brain imaging, functional connectivity, signal analysis and neural network modeling. Dr. Medvedev’s research focuses on neural mechanisms of cognitive processes in healthy participants as well as patients with various neurological disorders.

Near Real-time Computer Assisted Surgery for Brain Shift Correction using Biomechanical Models

K. Sun, T.S. Pheiffer, A.L. Simpson, J.A. Weis, R.C. Thompson, M.I. Miga

Brain deformation during surgery compromises the fidelity of image-guided tumor resection procedures.  This paper presents a comprehensive framework to intraoperatively account for volumetric brain deformations within image-guided surgery systems using only measurements of cortical surface ‘shift’…


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K SunK Sun
Dr. Sun became a Staff Engineer at Vanderbilt University from 2010-2013 and is now a Biomedical
Computation and Modeling Scientist at CFD Research Corporation, Huntsville, AL. She received her PhD in Bioengineering from Rice University in 2006.

T PheifferT Pheiffer
Mr. Pheiffer received his M.S. from Vanderbilt University in Biomedical Engineering in 2010. He is currently a Ph.D. Candidate in Biomedical Engineering at Vanderbilt University, and his research interests include image-guided surgery and ultrasound imaging.

A SimpsonA Simpson
Dr. Simpson recieved her PhD in Computer Science from Queen’s University in 2010. She joined the faculty at Vanderbilt University in November of 2009 and is currently a Research Assistant Professor in Biomedical Engineering. Her research interests include evaluation and validation methodologies for surgical navigation and the computation and visualization of measurement uncertainty in surgery.

J WeisJ Weis
Dr. Weis received his PhD in Biomedical Engineering from Vanderbilt University in 2011. He is currently a Postdoctoral Research Fellow at the Vanderbilt University Institute of Imaging Science and the Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN.

R ThompsonR Thompson
Dr. Thompson was recruited to Vanderbilt University’s Department on Neurological surgery in 2002. Dr. Thompson is currently the William F. Meacham Professor and Chairman of Neurosurgery, Director of Neurosurgical Oncology and Director of the Vanderbilt Brain Tumor Center.

M MigaM Miga
Dr. Miga is currently Professor of Biomedical Engineering, Radiology & Radiological Sciences, and Neurological Surgery. He also directs the Biomedical Modeling Laboratory and is co-founder of the Vanderbilt Initiative in Surgery and Engineering (VISE). The focus of his work is on the development of new paradigms in detection, diagnosis and treatment of disease through the integration of computational models into research and clinical practice.

Effective CPR Procedure with Real Time Evaluation and Feedback Using Smartphones

N.K. Gupta, V. Dantu, R. Dantu

Timely CPR can mean the difference between life and death. A trained person may not be available at emergency sites to give CPR. Normally, a 9-1-1 operator gives verbal instructions over the phone to a person giving CPR. In this paper, we discuss the use of smartphones to assist in administering CPR more efficiently and accurately. The two important CPR parameters are the frequency and depth of compressions…


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Scope Statement

We focus on innovative solutions to healthcare needs from biomedical engineering, clinical engineering, and medical communities that bridge the engineering and clinical worlds. JTEHM's unique scope is original work at the intersection of engineering and clinical translation.

The journal’s focus is interdisciplinary collaborations among researchers, healthcare providers, and industry. We publish results and best practices from these translational efforts and serve as a community hub for researchers, clinicians, and developers who are addressing challenges in technology development, commercialization, and deployment for better global healthcare. Our ultimate goal is to improve the practice of engineering in translational medicine and to serve as a focal point for the nascent community. Our interactive content includes video, lively commentary, blogs, and other features to engage our clinical and engineering communities.